1 . Title : Parameters affecting pharyngeal response to genioglossus stimulation in sleep
نویسنده
چکیده
3. Co-authors: T. Golibroda, OrtBraude College, Carmiel, Israel R. Oliven, Department of internal Medicine, Bnai-Zion Medical Center, Haifa, Israel A. Netzer, Department of Otolaryngology, Rambam Medical Center, Haifa, Israel L. Gaitini, Department of anesthesiology, Bnai-Zion Medical Center, Haifa, Israel A. Toubi, Department of radiology, Bnai-Zion Medical Center, Haifa, Israel A. Oliven, Department of internal Medicine, Bnai-Zion Medical Center, Haifa, Israel
منابع مشابه
Effect of genioglossus contraction on pharyngeal lumen and airflow in sleep apnoea patients.
The purpose of the present study was to quantify the mechanical effect of genioglossus stimulation on flow mechanics and pharyngeal cross-sectional area in patients with obstructive sleep apnoea, and to identify variables that determine the magnitude of the respiratory effect of tongue protrusion. The pressure/flow and pressure/cross-sectional area relationships of the velo- and oropharynx were...
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Pharyngeal collapsibility during sleep is believed to increase due to a decline in dilator muscle activity. However, genioglossus electromyogram (EMG) often increases during apnoeas and hypopnoeas, often without mechanical effect. 17 patients with obstructive sleep apnoea were anaesthetised and evaluated from termination of propofol administration to awakening. Genioglossus EMG, flow and pharyn...
متن کاملParameters affecting pharyngeal response to genioglossus stimulation in sleep apnoea.
Chronic stimulation of the hypoglossus nerve may provide a new treatment modality for obstructive sleep apnoea (OSA). In previous studies we observed large differences in response to stimulation of the genioglossus (GG). We hypothesised that both individual patient characteristics and the area of the GG stimulated are responsible for these differences. In the present study, we compared the resp...
متن کاملMechanical parameters determining pharyngeal collapsibility in patients with sleep apnea.
The relative impact of mechanical factors on pharyngeal patency in patients with obstructive sleep apnea is poorly understood. The present study was designed to evaluate parameters of the "tube law" on pharyngeal pressure-flow relationships and collapsibility in patients with obstructive sleep apnea. We developed a mathematical model that considered the collapsible segment of the pharynx to rep...
متن کاملElectrical stimulation of the hypoglossal nerve: a potential therapy.
Obstructive sleep apnea is characterized by recurrent episodes of pharyngeal collapse, which result from a decrease in pharyngeal dilator muscle tone. The genioglossus is a major pharyngeal dilator that maintains airway patency during sleep. Early studies in animal and humans have demonstrated that electrical stimulation of this muscle reduces pharyngeal collapsibility, increases airflow, and m...
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